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FLGR-242

FLGR-242 is a vendor code name, not an identified compound. It has no published literature in any scientific index, no entry in any chemical registry we can search, no agreed parent protein, no published sequence and no molecular weight anyone agrees on.

It is sold under the name of follistatin, described elsewhere as a modified follistatin fragment, and elsewhere again as an FSTL3 analogue — three descriptions that cannot all be true.

Best for

Nothing that can be stated from evidence. There is no published study of FLGR-242 in any species, no toxicology, no pharmacokinetics and no registered trial, so there is no population for which a benefit has been shown and no basis on which to describe a use. This entry exists because the compound is sold and people search for it, not because there is a case for it.

What to expect

Unknowable. No pharmacokinetic study of FLGR-242 exists in any species, so there is no measured time to peak, no duration and no half-life.

An extended half-life is claimed for it on the basis of an albumin-binding element; the published albumin-binding literature does not support the figures in circulation, and no measurement of this compound has ever been made.

Pairs with

Nothing, on any evidence basis. Combining an unidentified compound with anything else compounds the unknown rather than managing it — there is no characterised mechanism to predict an interaction from, and no way to attribute an effect or an adverse event to one input rather than the other.

Research protocol

No dose of FLGR-242 has ever been published, in any species, by any route — so nothing below is a recommendation, and this page invents nothing.

One protocol does circulate widely, and since it is what most people arrive here holding, it is worth setting out and checking rather than ignoring: 2.5 mg once a week for four weeks, then 5 mg weekly for eight, then 10 mg weekly for twelve. It carries no source, and no study of this compound exists to have produced one.

Three things about it are checkable by anyone. First, a milligram figure presupposes a known molecule: with no agreed identity, no published sequence and no molecular weight, “10 mg” describes a mass of powder, not a quantity of a named substance.

Second, it contradicts the marketing it travels with — the roughly 19-day half-life claimed for this compound would make weekly dosing accumulate to about 4.4 times the stated dose at steady state, so either that half-life claim is wrong or the weekly schedule is; nobody has measured either. Third, the arithmetic: vials are labelled 5 mg, so the final rung is two vials per injection, and the full 24 weeks comes to 34 vials — the escalation curve and the reorder curve are the same curve.

There is also no stated endpoint, no monitoring and no stopping rule anywhere in it.

Typical research dosing
Typical start2.5 mgweeks 1–4 · circulating figure, no published source5 mgweeks 5–12 · circulating figure, no published source10 mgweeks 13–24 · circulating figure, no published source
How often
Weekly
When
Morning
Route
Subcutaneous
Vial & water
5 mg vial in 1 mL = 5 mg/mL · 2.5 mg = 50 units on a U-100 syringe
Cycle
The circulating protocol escalates 2.5 mg/week for 4 weeks, then 5 mg/week for 8, then 10 mg/week for 12 — with no stated endpoint, no monitoring and no stopping rule. It has no published source, and no study of this compound exists to have produced one.
⚠ Research-compound safetyIDENTITY UNESTABLISHED — no published sequence, no agreed molecular weight, and no chemical-registry entry. Descriptions in circulation contradict each other on the parent protein (a follistatin-344 fragment, an FSTL3 analogue, or follistatin itself — these are not the same claim), and it is sold under the name of follistatin, a real protein whose literature is not evidence about this compound. Vendor certificates measure PURITY AND QUANTITY, never identity: the determined identity restates the label supplied with the sample, because no reference standard exists. Three certificates from one laboratory disagree — one is headed FLGR232 while its own mass-spectrometry trace says FLGR242, one records its batch number as the product code. An endotoxin pass is not a sterility test and not a safety clearance. The supplier safety data sheet is partly about a different molecule (oxytocin), contradicts itself on toxicology, and records the CAS number as "proprietary". No toxicology exists in either direction — an absent safety record is not a clean safety record. Not approved by any regulator, for any use, anywhere.

The same numbers the goodtides app and the Dose Calc use — a research reference, not a prescription. Responses are individual; research protocols start at the low end.

How it works

There is no mechanism to describe, and the reason is worth stating precisely: no molecule has been identified. A mechanism is a claim about how a specific structure interacts with a specific target, and FLGR-242 has no published structure.

The descriptions in circulation do not even agree on what the starting protein is. Three passages in it describe oxytocin, including an LD50 and a warning that women of childbearing potential should exercise extreme caution because the substance may induce uterine contractions; section 2 carries each of its entries twice, an oxytocin version beside a generic one, which reads as an oxytocin template only partly rewritten.

Searched on 6 September 2026 and re-checked in full on 11 September 2026, it returns zero records in PubMed, PubMed Central, Europe PMC (which indexes preprints and patents), OpenAlex, Crossref, PubChem's compound and substance databases, UniProt, ClinicalTrials.gov and DailyMed, across three spellings. The indexes are working — the bare token FLGR returns forty PubMed records, all of them about flgR, a sigma-54-dependent transcriptional activator controlling flagellar assembly in bacteria such as Campylobacter and Helicobacter, which has nothing to do with peptides or muscle.

What exists instead is a mechanism borrowed from a real protein. FLGR-242 is sold under the name follistatin, and follistatin biology is genuine and well characterised: follistatin (UniProt P19883, gene FST, 344 amino acids) binds and neutralises members of the TGF-beta superfamily including myostatin, the negative regulator of skeletal muscle mass, and follistatin gene therapy has been taken into human trials — a phase 1/2a study in Becker muscular dystrophy, published in Molecular Therapy in 2015.

None of that is evidence about FLGR-242. It is evidence about follistatin, and the two are connected only by a product name.

The compound is variously described as a modified fragment of follistatin-344 fused to an albumin-binding construct, as an FSTL3-derived analogue, and simply as follistatin itself. Follistatin-related protein 3 (UniProt O95633, gene FSTL3, 263 amino acids) is a different gene product with a similar name.

A fragment of a protein is not the protein. A compound with no agreed parent cannot have an agreed sequence, and without a sequence there is no molecular weight, no theoretical mass, and nothing for a laboratory to measure against.

The extended half-life attributed to an albumin-binding element is checkable, and the check does not support the claim. In the 2002 Journal of Biological Chemistry paper that established the albumin-binding strategy, an albumin-binding peptide fused to an antibody fragment extended that fragment's half-life 37-fold, to 32.4 hours in rabbits, and 26-fold, to 10.4 hours in mice — which the authors describe as 25 to 43 percent of the albumin half-life in those animals, not the carrier's own duration.

The mechanism does not hand a molecule albumin's lifetime, and multi-week figures quoted for an uncharacterised peptide on the strength of it claim considerably more than the strategy has been shown to deliver, in a species nobody has tested, for a molecule with no published structure to do the binding.

Four documents circulate in place of a literature, and we read all four on 11 September 2026. Three are certificates of analysis from MDx BioAnalytical Laboratory for BioLongevity Labs — a real laboratory, professionally produced documents carrying chromatography and mass-spectrometry traces, a vial photograph and a named signatory.

They report a single dominant peak, purities of 99.71 to 99.79 percent, about 5 mg of material against a 5 mg label, and endotoxin results under the stated threshold. Those are real measurements of purity and quantity.

They are not measurements of identity: in each certificate the determined identity restates the identity written on the vial that was sent, because no reference standard exists to compare against. Read together the three also disagree.

One is headed FLGR232 and carries CAS 3108438-94-1 while the mass-spectrometry trace printed inside it is captioned FLGR242. Another records its batch number as the string FLGR — a product code, not a lot — and gives receipt and reporting dates a year apart.

The CAS number appears on that one certificate and on neither of the others; it has a valid check digit, which is trivial to construct, and we found no matching record in PubChem's compound or substance databases or in Europe PMC. The fourth document, from the other vendor, is a safety data sheet rather than a certificate of analysis — a hazard-communication document supplied by the seller, not third-party analytical evidence — and it is partly about a different molecule.

That is evidence about the paperwork and not about the contents — nothing indicates the material is oxytocin — but it leaves the one document written to explain safe handling unreliable. The same sheet contradicts itself on toxicology, reasoning from a specific LD50 in section 2 while section 11 states that no acute toxicity data is available for this compound, and it records the CAS number as "Proprietary / research compound", which cannot be squared with the CAS printed on the other vendor's certificate.

Its molecular weight and sequence are deferred to the certificates, and the certificates carry neither.

One line on those certificates is read more generously than it should be. An endotoxin pass is not a sterility result and not a safety clearance; it tests for one class of bacterial breakdown product against a threshold, and says nothing about what else is in the vial.

None of this establishes that the vials are empty or that the material is dangerous. Something is in them, and three laboratory reports say that something is a single, highly pure substance of roughly the stated mass.

What no document establishes is what that substance is. An absent safety record is also not a clean safety record: there is no toxicology to cite in either direction, and the two are routinely confused in this market.

Pharmacokinetics
Half-life
NOT PUBLISHED, and not measurable without an identified molecule. No pharmacokinetic study of FLGR-242 exists in any species. Multi-week figures circulate on the basis of an albumin-binding element; the founding 2002 study of that strategy reached 32.4 hours in rabbits and 10.4 hours in mice, which its authors describe as 25 to 43 percent of the albumin half-life — not the carrier's own duration. Any number quoted for this compound is unverifiable.
Peak
No data. No pharmacokinetic measurement of this compound has been published in any species.
Absorption
No data. No absorption, distribution or route-comparison study exists.
Bioavailability
No data. No bioavailability figure has been published for this compound by any route.
References13
  1. FLGR-242 — PubMed search, no results (re-verified 11 September 2026)PubMed · 2026
  2. FLGR-242 — Europe PMC search, no results; this index covers preprints and patentseuropepmc.org · 2026
  3. FLGR-242 — ClinicalTrials.gov, no registered studiesClinicalTrials.gov · 2026
  4. UniProt P19883 — Follistatin (FST), human, 344 amino acidsuniprot.org · 2026
  5. UniProt O95633 — Follistatin-related protein 3 (FSTL3), human, 263 amino acids: a different gene productuniprot.org · 2026
  6. Albumin binding as a general strategy for improving the pharmacokinetics of proteins (J Biol Chem; the founding albumin-binding study)PubMed · 2002
  7. A phase 1/2a follistatin gene therapy trial for Becker muscular dystrophy (Molecular Therapy; real follistatin research, not a study of this compound)PubMed · 2015
  8. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis — the paper actually located at the coordinates cited in support of FLGR-242PubMed · 2015
  9. Certificate of analysis 261543 (QC261447), MDx BioAnalytical Laboratory — determined identity FLGR-242, purity 99.71%biolongevitylabs.com · 2026
  10. Certificate of analysis 261001 (QC260884) — headed FLGR232 with CAS 3108438-94-1; the mass-spectrometry trace inside is captioned FLGR242biolongevitylabs.com · 2026
  11. Certificate of analysis 260085 (QC260074) — batch number recorded as FLGR; received 7 January 2025, reported 9 January 2026biolongevitylabs.com · 2026
  12. Paramount Peptides safety data sheet for FLGR242 (6 pp., OSHA HCS format) — contains oxytocin hazard text in sections 2 and 11; records the CAS number as "Proprietary / research compound"paramountpeptides.com · 2026
  13. FLGR-242: we searched nine indexes and found nothing at all (goodtides)goodtides.shop · 2026
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This page is educational reference material about compounds studied in research settings. It is not medical advice, and nothing here is a recommendation to buy, possess, or use any compound. Research findings described are from published literature; individual compounds may not be approved for human use. Talk to a licensed clinician about anything that affects your health.